Dear Colleague, It is my pleasure to invite you to participate at ISCO2024 https://eventos.ull.es/isco-2024 It is the coming edition of a series of meetings known as "International Symposium on Combinatorial Optimization" (ISCO). Previous editions were in Tunisia (2010), Athens (2012), Lisbon (2014), Vietri (2016), Marrakesh (2018), Montreal (2020) and Paris (2022). Each edition consists of a 3-day international conference on Combinatorial Optimization preceded by a 2-day doctoral school. The coming 3-day conference will run from *22 to 24 May 2024*, preceded by a 2-day school on 20 and 21 May 2024. The venue will be the School of Mathematics at University of La Laguna (in La Laguna, Tenerife, Canary Islands, Spain). The aim of the ISCO2024 organizers is to create the best possible atmosphere in Tenerife to facilitate interaction between participants, selecting innovative submissions on all areas of Combinatorial Optimization to create an interesting scientific program, enriched with plenary talks by top motivational invited speakers, and complemented with attractive social activities. Feel free to distribute this invitation to everybody that could be interested in Combinatorial Optimization. Scientific presentations in the conference must follow a submission process, where we accept two types of proposals. "Regular papers" (up to 12 pages, *deadline extended to 10 January 2024*) and "Extended abstracts" (up to 3 pages, deadline is 15 February 2024). Each submission will be evaluated by the Program Committee and will be answered (accepted or rejected) by 15 March 2024. An author of each accepted submission must be registered at ISCO2024 before 31 March 2024. Accepted Regular Papers with a registered author will be published in a pre-conference proceeding (*LNCS* by Springer). You can find example of accepted regular papers of previous ISCO editions in https://link.springer.com/conference/isco <https://urldefense.com/v3/__https://link.springer.com/conference/isco__;!!D9dNQwwGXtA!VozJ2SkaBZe0SbKcnD1goqC8PB_NMrdQ5zOdDeW5LawschAMHusmdq3J5eZ6jy-5ypwjf1Ft-DUL3j3AE3vt$> or https://dblp.org/db/conf/iscopt/index.html <https://urldefense.com/v3/__https://dblp.org/db/conf/iscopt/index.html__;!!D9dNQwwGXtA!VozJ2SkaBZe0SbKcnD1goqC8PB_NMrdQ5zOdDeW5LawschAMHusmdq3J5eZ6jy-5ypwjf1Ft-DUL3pdeo7oZ$> Please, consider coming to ISCO2024. Kind regards, --A. Basu, R. Mahjoub, J.J.Salazar--